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There are arguably a pair of primary predisposing factors for gallstones. Heredity or genetics is one, and the body metabolic "profile" may or may not lend an individual to develop gallstones. Weight is another factor to consider, and heavier people are more likely to get gallstones than slimmer people. Between the two of these factors, most of those who present with gallstones will have a family history of them and be overweight. To a much lesser degree, diet may play a role.

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