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Because, the body thinks that the wrong/transfused blood type is "foreign". So therefore the body mounts an immune response to destroy those cells just like it would do to a bacterial or viral invasion.

4 types of blood groups AA, BB, AB, and O. AB is the universal accepter of any blood type because it already has A and B antigens and won't mount an immune response. O on the other hand is the universal donor. You can only give O blood type to a person with O blood. This is because they lack the A and B antigens and therefore the body will mount an immune response to it.

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15y ago

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