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The three primary players in the body's response to stress are the hypothalamus, the pituitary gland, and the adrenal glands, collectively known as the HPA axis. When a stressor is perceived, the hypothalamus releases corticotropin-releasing hormone (CRH), prompting the pituitary gland to secrete adrenocorticotropic hormone (ACTH). This hormone stimulates the adrenal glands to produce cortisol, the main stress hormone, which helps the body manage stress by regulating metabolism, immune response, and other vital functions. Together, these components orchestrate the physiological and behavioral responses to stress.

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2d ago

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