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(1) A lymph is transported back to the blood stream, the lymph nodes act as lymph "filters" Macrophages in the nodes remove and destroy microorganisms and other debri that enter the lymph from the loose connective tissues, effectively preventing them from being delivered to the blood and spreading to other parts of the body. (2) They help activate the immune system. Lymph nodes and other lymphoid organs are strategically located sites where lymphocytes encounter antigens and are activated to mount an attack against them.

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