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first of all joint damage as a result of chronic inflammation. If Gout is permitted to progress untreated attacks last longer and happen more often, possibly affecting several joins. These may become permanently damaged as a result.

One of the more serious complications that can occur are tophic formation. After years of hyperuricemia, (gout) permanent deposits of uric acid crystals may be formed in and around joints. These are called "Tophi" and can lead to disabling deformities and permanent damage to the kidneys.

Another is the formation of kidney stones these stones are made of 80% calcium, with the rest of various substances, including uric acid, cystine, and struvite)

And a risk of kidney failure crystals, protein, or other substances in the kidney can lead to kidney failure

If left untreated, tophi on the hands and feet can erupt and discharge chalky masses of crystals.

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14y ago

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