very much so.
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LDH stands for lactate dehydrogenase, an enzyme found in the body that plays a role in the conversion of lactate to pyruvate during energy production. Elevated levels of LDH in the blood can indicate tissue damage or certain medical conditions.
Elevated LDH levels can mean that you:(a) are experiencing hemolysis or the breakdown of red blood cells in your body tissues which contain LDH(b) if your levels remain high for up for several days, it could mean a myocardial infarction (heart attack) is on the way.(c) If your blood sample was incorrectly handled, the results may show that you have high levels of LDH even if you don't. This may be due to erythrocyte damage.(d) High levels of LDH may also indicate the presence of cancer cells, which destroy red blood cells found in your body tissues and release LDH into the blood stream.(e) In empyema, the LDH levels generally will exceed 1000 units per liter. Empyema is when fluid fills your lungs, leading to an infection.(f) viral meningitis (easily spreads through crowded population, such as college campuses and large urban areas)(g) encephalitis (caused by moquitoes that carry the disease)Source(wikipedia)
A LDH blood test measures the level of lactate dehydrogenase, an enzyme found in the body's tissues and organs. Elevated LDH levels may indicate tissue damage or diseases such as liver disease, heart attack, or certain types of cancer.
LDH enzyme (subtype 4H) is very abundant in red blood cells and heart muscle. In vit B12 deficiency there is high destruction of red cells in the bone marrow and in the blood vessels. As RBCs ruptures they release their inner content into the blood stream. So that's how LDH goes up in the blood.
Normal levels of lactate dehydrogenase (LDH) in the blood typically range from about 140 to 280 units per liter (U/L), although the exact reference range can vary slightly depending on the laboratory and specific testing methods used. LDH is an enzyme found in many tissues throughout the body, and elevated levels can indicate tissue damage or certain medical conditions. It's important to interpret LDH results in the context of other clinical findings and tests.
In my case, I was told "non-alcoholic fatty liver." High blood cholesterol may cause high SGOT/AST and a specific LDH "type" (they can tell from whence the LDH originates) may be elevated. If they said liver, then fatty liver is usually the culprit. Habitual alcohol or certain medication use may cause fatty liver as well. Losing weight is said to help lower those two. Lowering blood cholesterol is important to help the "fatty liver" lessen it's load. In my case, years pass and more bloodwork reveals the same, plus leukemia and lymphoma. I am in poor general health, so I think the high AST & LDH are from the fatty liver and not the cancers. A CBC will inform your doctor if there are abnormalities that would point him/her away from fatty liver.
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A red or gold-topped tube is typically used for collecting samples for LDH testing.
The color tube typically used for LDH testing is a light green or mint green tube, which contains lithium heparin as the anticoagulant. This tube is specifically designed to preserve enzyme activity for accurate LDH measurement.
LDL cholesterol levels are the calculation of bad levels in your body while HDL is considered to by the levels of good cholesterol in your body. Good cholesterol ratings can be maintained with proper exercise and diet.