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The alveolar walls can collapse due to several factors, including a decrease in surfactant production, which reduces surface tension and makes it harder for the alveoli to remain open. Conditions such as pneumonia, acute respiratory distress syndrome (ARDS), or lung fibrosis can also lead to inflammation and damage to the alveolar structure. Additionally, increased pressure from surrounding tissues or airways can contribute to alveolar collapse, known as atelectasis.

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