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Follicular lymphoma is primarily caused by genetic mutations that lead to the abnormal growth of B-cells, a type of white blood cell. One key factor is the chromosomal translocation involving the BCL2 gene, which prevents normal apoptosis (programmed cell death) and allows cancerous cells to survive longer than they should. While the exact cause of these genetic changes is not fully understood, environmental factors, immune system dysfunction, and certain infections, such as the Epstein-Barr virus, may contribute to the development of the disease.

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2mo ago

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