I have sarciodosis
what does it mean when my IGM is low at 28L
also called gamma globulin electrophoresis, or immunoglobulin electrophoresis, is a method of determining the blood levels of three major immunoglobulins: immunoglobulin M (IgM), immunoglobulin G (IgG), and immunoglobulin A (IgA).
Immunoglobulin G; it makes up 80% of the Immunoglobulin content in the bloodstream
There are five immunoglobulin classes (isotypes) of antibody molecules found in serum: IgG, IgM, IgA, IgE, and IgD. IgA (immunoglobulin A) IgD (immunoglobulin D) IgE (immunoglobulin E) IgG (immunoglobulin G) IgM (immunoglobulin M)
Low levels of immunoglobulin G (IgG) and immunoglobulin M (IgM) can indicate an issue with your immune system, such as a primary immunodeficiency or a response to chronic infections. Despite normal blood work in other areas, these specific immunoglobulin deficiencies can occur independently and may not show up in standard tests. It's important to discuss these findings with your healthcare provider, who may recommend further testing or evaluation to determine the underlying cause and appropriate treatment.
Normal range is between 700 and 1600.
The class of immunoglobulin to respond to the fist exposure of an antigen is immunoglobulin class M (IgM). While Immunoglobulin G (IgG) would predominate on the second exposure.
The immunoglobulin G (IgG) is the most important for humans; see also the link below.
Low levels of immunoglobulin G (IgG), immunoglobulin A (IgA), and immunoglobulin D (IgD) in the serum indicate potential issues with the immune system, such as immunodeficiency disorders. IgG is the most abundant antibody and plays a crucial role in fighting infections, while IgA is important for mucosal immunity, and IgD is involved in the activation of B cells. Low levels may increase susceptibility to infections and may require further evaluation by a healthcare professional to determine the underlying cause and appropriate management.
what is immunoglobulin for
The class of immunoglobulin that is produced in the primary immune response is Immmunoglobulin M (IgM). On secondary exposure, the class that predominates would be Immunoglobulin G (IgG).