46,XXY or XXY for males; see the link below.
If one of sex chromosomes is missing. Normal-XX Turner- XO
The most common type of chromosomal disorder is the Down syndrome caused by an added copy of chromosomes 21. More common chromosomal disorders are Klinefelter's syndrome and Turnerâ??s syndrome.
Klinefelter syndrome is a chromosomal condition that only affects males and is characterized by a male having an additional X chromosome (XXY) in cells. This chromosome abnormality occurs when there is an error in cell division, resulting in an extra copy of the X chromosome.
non disjunction of sex chromosomes
Yes, Klinefelter's syndrome is due to the XXY genotype.
non disjunction of sex chromosomes
Causes of Klinefelter SyndromeThe additional sex chromosomes in men with Klinefelter syndrome results from nondisjunction during meiosis and may have a paternal (50 to 60 percent) or maternal (40 to 50 percent) origin. This contrasts with Down syndrome, which is caused predominantly by maternal nondisjunction and inheritance of the extra chromosome 21 from the mother.
A few common causes for miscarriages are chromosomal abnormalities, incompetent cervixes, and polycystic ovary syndrome.
By definition Klinefelter's syndrome is genetically XXY. If there is any Y chromosome present, the baby will develop into a boy. Even if a baby had XXXXY, it would still turn out as a boy.
Klinefelterâ??s syndrome is the result of additional X genetic material in males and typically causes low testosterone levels, gynecomastia, and infertility. Though there are no documented famous people with this syndrome, some believe that George Washington may have been afflicted.
It could be a problem very early in development (during pregnancy). About 1/3 of all males with Klinefelter syndrome have other chromosome changes involving an extra X chromosome.This syndrome isn't considered an inherited condition.Klinefelter's syndrome is not hereditary. And males who have this disease are infertiled. It means that they can't produce offspring because they can make few sperms.
Various forms of cancers are caused due to accumulation of mutations. Some DNA viruses like papilloma, etc. can turn for lysogenic phase and cause cancer. Burkitt's lymphoma is another example (chromosomal aberrations). after cancer has stepped in it causes further mutations.