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The amount and duration of radiation exposure affects the severity or type of health effect.

Cancer is considered the primary health effect from radiation exposure.

Radiation can also cause changes in DNA (the blueprints) that ensure cell repair and replacement. Changes in DNA are called mutations. The mutations can be caused by exposure of the fetus in the uterus and affect only the individual who was exposed. Genetic mutations are passed on to offspring.

Health effects from 'acute' exposure to radiation usually appear quickly. These effects include burns and radiation sickness. Radiation sickness is also called 'radiation poisoning.' It can cause premature aging or death. Symptoms of radiation sickness are: nausea, weakness, hair loss, skin burns or diminished organ function.

Chemical properties of a radionuclide determine where health effects occur. Many organs require certain elements and can't make the difference between radioactive and non-radioactive forms of the element and accumulate it as rapidly as the other.

Examples:

The thyroid needs iodine to function normally, but can't tell the difference between stable and radioactive isotopes. As a result, radioactive iodine contributes to thyroid cancer more than other types of cancer.

Calcium, strontium-90 and radium-226 have similar chemical properties. Then, strontium and radium in the body tend to collect in calcium rich areas, such as bones and teeth. Then, they contribute to bone cancer.

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