Chronic Renal Failure
Chronic Renal Failure
Nephrons are the functional units of the kidney and can last a lifetime if they are not damaged or affected by disease. However, loss of nephrons can occur with aging or due to certain medical conditions.
Polycystic kidney disease is an inherited disorder that causes cysts to be formed on the nephrons, or functioning units, of the kidneys
Bright's Disease affects the kidney, including the nephrons and glomeruli. However, Bright's Disease is but one of many which affect the glomeruli of the kidney.
A gradual loss of nephrons is called chronic kidney disease. This condition typically progresses slowly over time, leading to a decrease in kidney function and potential complications. Treatment aims to slow the progression and manage symptoms.
Nephrons are the fundamental functional units of the kidneys, playing a crucial role in filtering blood to remove waste products and excess substances, thereby maintaining homeostasis. Each kidney contains approximately one million nephrons, which regulate electrolyte balance, blood pressure, and fluid levels. By producing urine through processes of filtration, reabsorption, and secretion, nephrons help control the body's chemical composition and overall health. Their proper function is vital for preventing conditions such as kidney disease and hypertension.
Marco Polo handled his disease by remaining in Badakhshan for a year until it passed.
complication
This means disease of the kidney cells (nephrons) themselves. It usually implies less than optimal capacity to process waste (such as urinary creatinine).
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About 20% still have active disease requiring ongoing treatment after five years, and about 30% have inactive disease but some remaining muscle weakness.
In stage 5 renal failure, also known as end-stage renal disease (ESRD), approximately 90-95% of nephrons are lost. This significant loss severely impairs kidney function, leading to the need for dialysis or kidney transplantation for survival. At this stage, the kidneys are unable to adequately filter waste and maintain fluid and electrolyte balance.