The disease is called as 'Addison's disease'. In developing countries, you get this disease very commonly, as a result of injudicious use of corticosteroids by quacks, leading to suppression of hypothalamo-pituitory-adrenal axis.
Some common adrenal gland disorders include Addison's disease, Cushing's syndrome, and congenital adrenal hyperplasia. Addison's disease is characterized by insufficient production of adrenal hormones, while Cushing's syndrome is marked by excessive levels of cortisol. Congenital adrenal hyperplasia involves a group of genetic disorders affecting the adrenal glands' ability to produce hormones like cortisol and aldosterone.
Addison's disease is a disorder that causes your body produces insufficient amounts of certain hormones produced by the adrenal glands. In Addison's disease, your adrenal glands produce too little cortisol, and often not enough of aldosterone as well. It is also called Also called adrenal insufficiency or hypocortisolism.
Addison's disease
The adrenal cortex, which is a part of the adrenal gland, produces cortisol. Cortisol is a hormone that is involved in the body's response to stress and helps regulate metabolism, blood sugar levels, and inflammation.
The adrenal glands produce steroid hormones such as testosterone, aldosterone, and cortisol. The medulla is the interior portion of the adrenal glands and it produces epinephrine and norepinephrine.
Addison's disease is the result of inadequate secretion of cortisol by the adrenal cortex.When your adrenal glands don't produce enough cortisol, it is called adrenal insufficiency. It can also be referred to as Addison's disease or hypocortisolism.
The steroid hormones produced by the adrenal cortex exhibit feedback inhibition on ACTH production, therefore a low concentration of corticosteroids (as seen in Addisons disease) will not exhibit this feedback inhibition. Without this inhibition, ACTH levels are not regulated and therefore rise.
adrenal glandEither of two small triangular endocrine glandslocated on top of the kidneys. In humans, each gland weighs about 0.18 oz (5 g) and consists of an inner medulla, which produces the catecholamine hormones epinephrineand norepinephrine, and an outer cortex (about 90% of the gland), which secretes the steroidhormones aldosterone, cortisol, and androgens(the last two in response to acthfrom the pituitary-gland). Diseases of the adrenal glands include pheochromocytoma (a tumour of the medulla) and the cortical disorders addison-s-disease, adrenal hypertrophy, cushing-s-syndrome, and primary aldosteronism.
Addison disease is a hormonal system disease that is caused by a dysfunction of the adrenal cortex glands, and involves the lack, or low amounts of certain hormones: cortisol, androgen, and aldosterone. It is mostly due to a lack of adequate amounts of cortisol and is often associated with bronzing of the skin.
Addison's diseaseI think it is Addison's disease
The pituitary hormone that targets the adrenal cortex is adrenocorticotropic hormone (ACTH). It stimulates the adrenal cortex to produce and release cortisol, which is important for regulating metabolism, immune response, and the body's response to stress.
Addison's disease, also known as primary adrenal insufficiency, is a disorder in which the adrenal glands do not produce enough hormones, particularly cortisol and aldosterone. This condition can lead to symptoms like fatigue, weight loss, low blood pressure, and hyperpigmentation of the skin. Treatment typically involves hormone replacement therapy, such as glucocorticoids (like hydrocortisone) to replace cortisol, and sometimes mineralocorticoids (like fludrocortisone) to replace aldosterone, helping to manage symptoms and maintain electrolyte balance. Regular monitoring and adjustments to medication are essential for effective management.