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The quinolones are a group of antibiotics. They are considered broad spectrum antibiotics in that they can treat a wide variety of things, and are broken down into four generations based on their specific sensitivities:

First generation quinolones have a wide gram positive spectrum, but the gram negative coverage is pretty narrow. They are not used much anymore because they tend to have toxicity issues.

Second generation quinolones have a little wide gram negative spectrum, but a little narrower gram positive.

Third generation quinolones are like second generation but can also work against Staph.

Fourth generation quinolones are like third generation but have a wider gram positive coverage and can also treat anaerobes.

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14y ago

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