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"discolysis" literally means 'destruction of the disc', specifically, a disk between two vertebra.

There are studies being performed, primarily outside the U.S., involving the use of Ozone, (O2 + O = O3), as an alternate treatment of a herniated disc. The half-life of ozone is barely a few seconds. In this time it reacts with surrounding substances, water, or antioxidants where injected to become O2. O3 is injected into the disc, or around the disc, to treat the herniation. It reduces the disc size, i.e "discolysis", which is the goal of a disectomy or microdisectomy performed via surgery, to take pressure off surrounding nerves. Ozone discolysis is minimally invasive as compared to the surgery, and reduces the disc volume via an alternate means.

Intradiscal Injection, which is performed in the operating room under sedation and monitoring fluoroscopy. Typical use is 1 or 2 injections.


Paravertebral Injection, which needs no operating room, no sedation, no fluoroscopy control, but does require repeated administration, usually 10-12.


The alteration that the O3 exerts on the the local "free radicals - antioxidants" with production of H2O2, leading to amend various cytokines and pro-inflammatory substances (Bocci, 2002). The best evidence of this effect are pathological studies on samples of intervertebral disc, which has been objectified that ozone causes the collagen and proteoglycans that form the nucleus pulposus disc to release water. This results in cellular dehydration and degeneration of the matrix, which is replaced by fibrous tissue after about 5 weeks, leading to a reduction in disk volume (Iliakis, 2001) (Andreula, 2003), and thereby improving the mechanical components on nerve, and perhaps on the microcirculation of the same, which further enhance its vascular support.

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