Bilirubin jaundice and urobilinogen are both related to the metabolism and breakdown of hemoglobin. When red blood cells are destroyed, hemoglobin is converted into bilirubin, which can accumulate in the blood and cause jaundice when levels are elevated. Urobilinogen is a byproduct of bilirubin metabolism that occurs in the intestines, where bilirubin is converted by gut bacteria. Thus, both conditions reflect the body's processing of bilirubin, with jaundice indicating high bilirubin levels and urobilinogen providing insight into bile and liver function.
Hemolytic jaundice - excessive breakdown of red blood cells leads to a corresponding increase in conjugated bilirubin excreted by the liver, converted to urobilinogen in the intestines, and more urobilinogen being reabsorbed in the intestines which gets excreted in the urine.
Bilirubin and urobilinogen are both products related to the breakdown of hemoglobin. Bilirubin is produced in the liver from the breakdown of red blood cells and is normally excreted in bile. When bilirubin reaches the intestines, it is converted by bacteria into urobilinogen. In urine samples, the presence of bilirubin indicates liver dysfunction or obstruction, while urobilinogen levels can reflect liver function and gut health, as they are usually reabsorbed and excreted in urine.
It's the bilirubin found in an urinalysis.
Urobilinogen refers to the presence of bilirubin in the urine. Bilirubin is an enzyme that comes from the liver, and if it shows up in urine, that typically means that a person has a serious illness. The illness could be anything from gallstones to anemia, since bilirubin in the urine could be caused by many different things.
Bilirubin is the pigment that makes feces brown."Failure of the liver cells to excrete bile, or obstruction of the bile ducts, can cause an increased amount of bilirubin in the body fluids and thus lead to obstructive or regurgitation jaundice.Another type of jaundice results from excessive destruction of erythrocytes (hemolytic or retention jaundice). The more rapid the destruction of red blood cells and the degradation of hemoglobin, the greater the amount of bilirubin in the body fluids.Most bilirubin is excreted in the feces. A small amount is excreted in the urine as urobilinogen."answers.com
Urobilinogen
Urobilinogen is formed in the intestines from the breakdown of bilirubin, which is a byproduct of the degradation of hemoglobin from old red blood cells. Bilirubin is converted by intestinal bacteria into urobilinogen. Some of this urobilinogen is reabsorbed into the bloodstream and eventually excreted in urine, while the rest is converted to stercobilin and eliminated in feces, giving stool its characteristic brown color.
Urobilinogen: Urobilinogen is normally present in urine at concentrations up to 1.0mg/dl. A result of 2.0mg/dl represents the transition zone from normal to abnormal and the patient and or urine specimen should be evaluated further for hemolytic and hepatic disease. Evaluation of both the bilirubin and urobilinogen results helps in the differential diagnosis of jaundice, as well as other liver and biliary disorders.
Bilirubin is a yellow pigment produced during the breakdown of red blood cells, and its accumulation in the bloodstream is what causes jaundice. The severity of jaundice is directly related to the level of bilirubin; higher bilirubin levels typically result in more pronounced yellowing of the skin and eyes. Jaundice occurs when bilirubin levels exceed the normal range, indicating potential liver dysfunction, hemolysis, or bile duct obstruction. Monitoring bilirubin levels is essential for diagnosing and managing the underlying causes of jaundice.
Increased urobilinogen with normal serum bilirubin levels can indicate a few potential conditions, such as hemolysis, where there is increased breakdown of red blood cells leading to higher production of urobilinogen from bilirubin in the intestines. It may also suggest liver dysfunction or increased intestinal absorption of urobilinogen. However, since bilirubin levels remain normal, significant liver impairment or obstruction is less likely. It's important to correlate these findings with clinical symptoms and further diagnostic testing for accurate interpretation.
jaundice the normal serum bilirubin level is 0.5 to 1.5mg%. jaundice occurs when the bilirubin level exceeds 2mg%. the increased blood level of bilirubin is called hyperbilirubinemia. excess bilirubin from blood diffuses into the tissues, skin and mucous membrane, colouring them yellow. this condition caused by overflow of bilirubin is called jaundice.
Newborn jaundice is caused when there are high bilirubin levels in the blood.