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Short answer:

Insulin.

Long answer: Normally, blood glucose levels are tightly controlled by Insulin, a hormone produced by the pancreas. Insulin lowers the blood glucose level. When the blood glucose elevates (for example, after eating food), Insulinis released from the pancreas to normalize the glucose level. In patients with Diabetes, the absence or insufficient production of Insulin causes hyperglycemia. Diabetes is a chronic medical condition, meaning that although it can be controlled, it lasts a lifetime.

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