Most studies focus on autism or autism spectrum disorders, rather than Asperger's Syndrome specifically. More than one chromosome is linked to autism spectrum disorders. The chromosomes involved according to various studies are listed below.
A few sites providing information on the genetics of autism highlight results about several of the chromosomes:
Exploring Autism: A Look at the Genetics of Autism
Autism is Likely to Be Linked to Several Genes
There are also articles that could be available through your library's electronic database subscriptions or available in journal form from an academic library. Some hospitals also subscribe to electronic databases with medical information and allow public access.
Autism: In Search of Susceptibility Genes - abstract (August, 2002)
Links to the articles at ScienceDaily.com about studies on certain chromosomes are provided below in the related links section.
Chromosome 2:
Researchers Identify First Gene Variant That Appears to Increase Risk of Autism in Significant Portion of the Population (April 1, 2004)
Chromosomes 3, 4, 7, and 11:
Different Genes May Cause Autism in Boys and Girls (July 31, 2006)
Chromosome 7:
New Genetic Link to Autism Discovered by Studying Speech (Jan 11, 2008)
New Protein Implicated in Autism (Mar 27, 2007)
Chromosomes 7 and 21:
Study Links Regions of Two Chromosomes to Susceptibility for Type of Autism (June 9, 2005)
Chromosome 11:
Gene That May Lead to Autism Identified (Mar 14, 2007)
Chromosome 13:
Study Points to Chromosome Site of Autism Gene (Dec 3, 1999)
Chromosomes 15 and 22:
Gene Screen to Identify Causes of Autism (Oct 17, 2008)
Chromosome 16:
Novel Chromosome Abnormality Appears to Increase Risk of Autism (Jan 10, 2008)
Recurrent Genetic Deletion Linked to Autism, Study Shows (Jan 10, 2008)
Chromosomal Abnormalities Play Substantial Role in Autism (Jan 22, 2008)
Chromosome 17:
UCLA Scientists Pinpoint Region of Autism Gene on Chromosome 17 (May 4, 2005)
It is a mutated gene called PKD1 located on chromosome 16.
Lowe syndrome is caused by a mutated gene on the X sex chromosome. Because it is X-linked, it occurs almost exclusively in males.
The defective gene in Hurler syndrome is located on chromosome 4. This gene carries instructions for making an enzyme called alpha-L-iduronidase, which is essential for breaking down certain complex molecules in the body. When this gene is mutated, the enzyme is deficient, leading to the accumulation of harmful substances in the cells.
In the female carrier of a sex-linked disorder, there would typically be one normal allele and one mutated allele for the gene associated with the disorder on the X chromosome. This is because females have two X chromosomes, and one copy of the X chromosome with the mutated allele can be masked by the normal allele on the other X chromosome.
Yes. It is found as a mutation on the X chromosome (a sex chromosome) so it is sex linked. The gene for Fragile X is carried on the X chromosome. Because both males (XY) and females (XX) have at least one X chromosome, both can pass on the mutated gene to their children.
Hunter's disease is inherited in an X-linked recessive pattern. This means the mutated gene that causes the disease is located on the X chromosome, and males are more commonly affected because they only have one X chromosome. Females can carry the mutated gene but are typically unaffected due to having a second X chromosome that can compensate.
Females carry two X chromosomes; males only carry one. A female carrier carries a defective recessive allele for a gene on the X chromosome. Thus, the female will not be affected because she still has a copy of the dominant allele. However, if she has any male children, that child will be affected because males inherit their X chromosome from their mothers.
Inherited on a sex chromosome, genetic disorders such as color blindness and hemophilia are caused by mutations in specific genes located on the X chromosome. These disorders are more commonly seen in males because they have only one X chromosome, making them more likely to express recessive X-linked traits. Females, with two X chromosomes, are typically carriers of the mutated gene but may not exhibit the disorder unless they inherit two copies of the mutated gene.
nucleus → chromosome → gene
yes , autism is caused by a dominant gene
Duchenne muscular dystrophy is inherited as an X-linked recessive genetic disorder, meaning the gene mutation that causes the condition is located on the X chromosome. Since boys have only one X chromosome inherited from their mother, they are more likely to develop Duchenne muscular dystrophy if they inherit the mutated gene. Girls have two X chromosomes, so even if they inherit one mutated gene, they often have a second normal X chromosome that can compensate for the mutation.
Smallest to largest: Gene (a place on a chromosome); chromosome (there are 46 in human cells); and DNA (because it accounts for all the genetic material in a cell).