The recipient's immune system will detect the difference between the two sets of antigen and start a rejection response to kill the donated tissue.
Tissue typing is done to match organ or bone marrow donors with recipients to minimize the risk of rejection. It involves analyzing specific proteins on the surface of cells to find the best match for a successful transplant.
It is estimated that it takes an average of one to two years to receive a suitable donor lung, and the wait is made less predictable by the necessity for tissue match.
If they are not exact as possible, the person receiving the blood or tissue or organ will reject it as foreign (doesn't belong).
tissue match, blood type, size of the organ, length of time on the waiting list, immune status, and the geographical distance between the recipient and donor
Physicians match human leukocyte antigens (HLAs) between the donor and recipient. HLAs are found on the surface of cells and are essential in identifying foreign tissues. Matching HLAs helps reduce the risk of rejection in organ transplant recipients.
There is no legal restriction on cross-race organ donation. However, since organ tissue types are driven by genetics, it is unlikely that donors and recipients of different races would match.
The donor can be a twin (best match), a sibling, or a person who is not related at all.
Because if it is not complatible the recipiant will mount an immune response against the blood cells in the donated blood and so clott it up creating a massive risk of blocking a major vessel and causing an MI or stroke.
To test for bone marrow donor eligibility, individuals can undergo a simple blood test to determine their human leukocyte antigen (HLA) type. This test helps match donors with recipients to increase the likelihood of a successful transplant. Additionally, potential donors will also undergo a physical exam and medical history review to ensure they are in good health and able to donate.
Blood tests have to be done to determine a match.
If the blood group is a match, and the donor wasn't sick, you'll be OK.
They have a National Marrow Donor registry that can help you find out if you are capable of being a donor. There is a list of qualifications you must pass to be considered a donor. If you qualify, they can send a simple test kit to your home that you mail back with a saliva sample.