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Hypercalcemia in the myocardium can lead to several detrimental effects on cardiac function. Elevated calcium levels can increase myocardial contractility initially, but prolonged hypercalcemia may result in impaired relaxation and diastolic dysfunction. This disruption can lead to arrhythmias, as the heart's electrical conduction system becomes affected, potentially causing irregular heartbeats or increased risks of cardiac arrest. Additionally, high calcium levels can contribute to vascular calcification, further complicating cardiovascular health.

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