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Malformed red blood cells, such as those seen in sickle cell disease, can obstruct blood flow and reduce the cells' ability to carry oxygen effectively. This leads to decreased oxygen delivery to tissues and organs, causing symptoms like pain, fatigue, and organ dysfunction. The blockages can also result in increased risk of complications, such as infections and stroke, due to impaired circulation. Overall, the interference with oxygen supply can significantly impact overall health and well-being.

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1mo ago

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