Serum calcium levels may be used to test for abnormalities in the kidneys. Low calcium levels can be an indication of a kidney disease. Likewise, thyroid and parathyroid diseases also are possible when there is an abnormal serum calcium level.
yes
measured serum calcium + (40-serum albumin)/50
False
Hypocalcemia ( a low serum calcium level), not hypercalcemia ( a high serum calcium level), tends to cause muscle spasm and in severe cases may lead to muscle tetany.
Low globulin can be due to immune deficiency associated with decreased antibody production. This would also account for lower total protein (because globulin is a protein), however it would not account for the low calcium level. Calcium is bound to protein in the blood, so low protein can be associated with a spruriously low calcium (i.e. a calcium number that is low without actual calcium deficiency). This may be the case if the albumin (another protein) is low, and there is a formula to correct calcium for low albumin, where: Corrected Calcium = (0.8 * (Normal Albumin - Pt's Albumin)) + Serum Ca Alternatively, an ionized calcium level can be checked and will be normal if the serum calcium was only low due to low albumin. Without knowing the clinical context (which would be very helpful), the most likely single explanation for low globulin, low total protein, and low serum calcium is protein nutritional deficiency. In this case, the body is overall protein deficient and so it is not uncommon to find a decrease in all protein levels (especially if severe). In this case, the low serum calcium is due to low albumin, as above. This can be further explored by checking a pre-albumin level (typically low if protein deficiency due to poor diet). You should talk to the physician who orderd the tests for a better answer, as only he or she knows why the tests were ordered and can interpret them in the appropriate clinical context.
Hypocalcemia is a medical condition in which there are low serum calcium levels in the blood. It is most frequently caused by hyperparathyroidism.
PTH is released when the body senses low serum calcium levels. PTH does everything in its power to increase serum calcium- it rips it from bone, increases its absorption from food, increases VIT D production (which also aids calcium absorption) and reduces its excretion from the body in urine. It therefore reduces urinary calcium.Above it was stated that PTH increases vit D production.This is wrong. Exposure of the skin to sunlight when the angle isn't too low and certain foods and supplements increase vit D. When serum calcium is low, PTH is sent by the parathyroids to signal vitamin D to activate itself and enable calcium absorption. When there is sufficient dietary calcium and vitamin D, serum calcium rises appropriately, and PTH is then decreased. When there is not enough dietary calcium and vitamin D, PTH can't get the calcium it needs. PTH then goes to the kidneys to look for temporarily stored calcium. If there isn't enough there, it goes to the bone to get the calcium there. Urinary calcium is from excess calcium that is absorbed into the blood with help from vitamin D (and thyroid) or absorbed when the bone is broken down. I learned that when urinary calcium is very high (above 300), PTH is high, but serum calcium is normal, this may indicate primary hyperparathryoidism even if serum calcium is normal. Good luck finding a doctor who will look further into primary hyperparathyroidism for patients without high serum calcium, regardless of high PTH and high urine calcium.
Do you mean an endocrine gland that can lower calcium level? If this is your question, the answer is thyroid gland. It produdes calcitonin that lowers calcium level opposing the effect of parathyroid gland which increases calcium level.If you mean, a condition that is characterized by low level of calcium in blood, it is called hypocalcemia.
Serum calcium will be depleted in advances osteoporosis. Calcium mostly resides in the bones. In osteoporsosis, the bone is being broken down faster than the body can rebuild it. This causes calcium stores to go from the bones and into the blood stream. Serum calcium is the measure of calcium in the blood, not what is in the bones.
The parathyroid glands and the thyroid gland are responsible for the maintenance of serum calcium levels. The parathyroid gland secretes parathyroid hormone (PTH), which increases serum calcium levels by stimulating calcium release from bones and increasing calcium absorption in the intestines. The thyroid gland secretes calcitonin, which helps regulate calcium levels by inhibiting the release of calcium from bones.
Oral phosphates can lower serum calcium levels, but the long-term use of this approach is not well understood.