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malaria is caused by a protozoan parasite called Plasmodium. The parasite infects the liver cells and red blood cells of the host. One part of the life cycle involves the formation of male and female gametocytes in the hosts blood. The gametocytes are ingested with the blood-meal when a mosquito bites the person. The gametocytes unite and form a zygote, which grows into the "adult" form of the parasite in the mosquito. This adult form (sporozoite) can infect another person when that mosquito bites someone else.

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