a person dying who donates a liver to a dying person
It is possible to transplant part of a liver from a living donor and have both donor and recipient survive.
The donor liver is placed in a different site, but it still has to have the same connections.
Two sections of a donor liver have been enough to save a patient in liver failure, especially if the patient is a child.
Replacement of a whole diseased liver by a healthy donor liver.
Depends on if it's a live donor or a dead donor. With a live donor only part of the liver is harvested for transplantation, and the remaining part will grow back to (close to) its original size within weeks.
He will go on a waiting list for a cadaver donor liver. He will get the transplant and live for his expected life-span. If no cadaver liver donor is available, they will treat him symptomatically and try to find a living donor among relatives who are compatible. If none is found, his long-term prognosis is not good. Half a liver from a living donor will regenerate and both the donor and the recipient will have an entire liver after a few months.
The list of living donor organs is shorter because not all organs can be donated while the donor is alive, due to the complexity of the organ and the impact on the donor's health. The most commonly donated organs from living donors are the kidney and liver, as they are organs that a person can live without or regenerate. Other organs, such as the heart or lungs, are not commonly donated from living donors due to the high risk involved.
Orthotopic transplantation is the replacement of a whole diseased liver with a healthy donor liver.
Liver transplantation is a surgery that removes a diseased liver and replace it with a healthy donor liver.
When an orthotopic transplantation is performed, a segment of the inferior vena cava attached to the liver is taken from the donor as well.
Liver transplant compatibility between donor and recipient is primarily determined by blood type, as matching ABO blood groups is crucial for reducing the risk of rejection. Additionally, the size of the donor liver must be appropriate for the recipient's body size. Human leukocyte antigen (HLA) matching, while less critical than in kidney transplants, can also play a role in compatibility. Furthermore, the overall health and medical history of both the donor and recipient are assessed to ensure the best possible outcome.
There is a high risk of tumor recurrence and metastases after transplantation.