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A presynaptic terminal is the part of a neuron that releases neurotransmitters into the synaptic cleft during neurotransmission. Located at the end of an axon, it contains synaptic vesicles filled with these chemical messengers. When an action potential reaches the presynaptic terminal, it triggers the release of neurotransmitters, which then bind to receptors on the postsynaptic neuron, facilitating communication between neurons. This process is essential for the functioning of the nervous system.

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What is The process by which the neurotransmitter substance leaves the presynaptic terminal button is called?

Leaves the presynaptic neuron, activates ion channel


The sites where a chemical substance is transmitted from the presynaptic terminal of an axon to the postsynaptic membrane of a muscle fiber are called?

The sites where a chemical substance is transmitted from the presynaptic terminal of an axon to the postsynaptic membrane of a muscle fiber are called neuromuscular junctions. At these junctions, the neurotransmitter acetylcholine is released from the presynaptic terminal and binds to receptors on the postsynaptic membrane, initiating muscle contraction.


What ion causes presynaptic vesicle to fuse to axon membrane?

The calcium ion is responsible for causing the presynaptic vesicle to fuse to the axon membrane in a process called exocytosis. When an action potential reaches the presynaptic terminal, calcium ions enter the terminal and trigger the fusion of the vesicle with the axon membrane, releasing neurotransmitters into the synaptic cleft.


What sequence of events occurs when an action potential arrives at the presynaptic terminal?

When an action potential arrives at the presynaptic terminal, voltage-gated calcium channels open, allowing calcium ions to enter the cell. The influx of calcium triggers the release of neurotransmitter vesicles from the presynaptic terminal into the synaptic cleft. These neurotransmitters then bind to receptors on the postsynaptic membrane, leading to changes in the postsynaptic cell's membrane potential.


What portion of a neuron forms the presynaptic neuronal membrane?

The axon terminals of a neuron form the presynaptic neuronal membrane. These structures contain synaptic vesicles that store neurotransmitters for release at the synapse.


Describe the structure of a synapse?

The synapse consists of two main parts that allow one neuron to communicate with another: 1) the presynaptic terminal located at the end of an axon; and 2) the postsynaptic terminal located on the dendrite of another neuron. The presynaptic terminal is where neurotransmitters are stored and released from. The postsynaptic terminal is the recipient side of the synapse. Neurotransmitters released from the presynaptic terminal will diffuse across the synaptic cleft and bind to receptors located on the surface of dendritic spines.


What ion must flow into the presynaptic cell in order for it to release neurotransmitter?

Calcium ions (Ca²⁺) must flow into the presynaptic cell for neurotransmitter release. When an action potential reaches the presynaptic terminal, voltage-gated calcium channels open, allowing Ca²⁺ to enter the cell. This influx of calcium triggers the fusion of neurotransmitter-containing vesicles with the presynaptic membrane, leading to the release of neurotransmitters into the synaptic cleft.


What are the six major components of the synapse?

The six major components of the synapse are the presynaptic terminal, synaptic vesicles, neurotransmitters, synaptic cleft, postsynaptic membrane, and receptor sites. The presynaptic terminal contains synaptic vesicles filled with neurotransmitters that are released into the synaptic cleft when an action potential arrives. The neurotransmitters then bind to receptor sites on the postsynaptic membrane, facilitating communication between neurons. The synaptic cleft is the gap between the presynaptic and postsynaptic neurons, where the transmission occurs.


The botulinus toxin that causes botulism acts by?

Botulinus toxin blocks the release of acetylcholine from the presynaptic terminal. This is a total blockage of neuronal transmission.


What is an autoreceptor?

An autoreceptor is a receptor which is situated in the terminal of a presynaptic nerve cell, sensitive to neurotransmitters released by the neuron in whose membrane the autoreceptor sits.


How does neurotransmitters initiate depolarization?

Let's picture a presynaptic neuron, a synaptic cleft, and a postsynaptic neuron. An action potential reaches the terminal of a presynaptic neurone and triggers an opening of Ca ions enters into the depolarized terminal. This influx of Ca ions causes the presynaptic vesicles to fuse with the presynaptic membrane. This releases the neurotransmitters into the synaptic cleft. The neurotransmitters diffuse through the synaptic cleft and bind to specific postsynaptic membrane receptors. This binding changes the receptors into a ion channel that allows cations like Na to enter into the postsynaptic neuron. As Na enters the postsynaptic membrane, it begins to depolarize and an action potential is generated.


What region of the cell secretes neurotransmitters?

Neurotransmitters are typically synthesized and stored in the synaptic vesicles of the presynaptic terminal, which is located at the end of the neuron. When an action potential arrives, these vesicles release neurotransmitters into the synaptic cleft to communicate with the postsynaptic neuron.