What is an antinuclear antibody test used to evaluate?

Answer 1

We normally have antibodies in our blood that repel invaders into our body, such as virus and bacteria microbes. Antinuclear antibodies (ANAs) are unusual antibodies, detectable in the blood, that have the capability of binding to certain structures within the nucleus of the cells. The nucleus is the innermost core within the body's cells and contains the DNA, the primary genetic material. ANAs are found in patients whose immune system may be predisposed to cause inflammation against their own body tissues. Antibodies that are directed against one's own tissues are referred to as auto-antibodies. The propensity for the immune system to work against its own body is referred to as autoimmunity. ANAs indicate the possible presence of autoimmunity and provide, therefore, an indication for doctors to consider the possibility of autoimmune illness.

Answer 2

Autoimmune disorders may be diagnosed utiliziting blood tests that measure for specific diseases. For example, individuals with systemic lupus erythematosus will have a positive ANA or antinuclear antibody test.

Answer 3

The antinuclear antibody test looks for a group of autoantibodies that attack substances found in the center (nucleus) of all cells. It is useful as a screen for many autoantibodies associated with diseases that affect the entire body (systemic diseases).

Answer 4

Antinuclear antibodies-- Autoantibodies that attack substances found in the center, or nucleus, of all cells.

Answer 5

autoimmune or rheumatic disease, particularly systemic lupus erythematosus (SLE).