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An Endocrine Axis is a specific network composed of the set of neurons that complete an entire hormonal cycle (I.E. the hypothalamus takes up dopamine--which is produced in the liver-- in the form of L-Dopa and reconverts it into Dopamine which is then be released into the hypothalamic-pituitary Axis and inhibits the release hormones like prolactin.)

In this case the hypothalamus and the pituitary form an axis with respect to the trajectory of effect of Dopamine.

Hope this gives you an idea.

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