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An effective engineering control to prevent the transmission of tuberculosis (TB) is the installation of negative pressure ventilation systems in healthcare settings, particularly in rooms designated for TB patients. This system helps to ensure that air flows into the room but not out of it, effectively containing airborne pathogens within the space and reducing the risk of exposure to healthcare workers and other patients. Additionally, high-efficiency particulate air (HEPA) filters can be used to further purify the air, capturing TB bacteria and improving overall air quality.

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