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A Sickle Cell is a type of Red Blood Cell (RBC) seen in the Sickle Cell Disease. This disease has an abnormal Hemoglobin molecule, termed Hemoglobin S. This is due to a point mutation in the Beta-Globin Gene on chromosome 11. The disease itself is homozygous and recessive so one can have the trait and not have the disease if one of the parents have it. The patients with this disease have lifelong hemolytic anemia and increased susceptibility to infections.
As for how the cells came to be called Sickle Cells, one has to understand the molecular structure of the Globin (protein) portion of Hemoglobin. In this disease, a polar amino acid (Glutamate) is replaced by a non polar amino acid (Valine) in the Globin molecule, thus reducing its overall charge. This also causes a protrusion in the Hemoglobin surface that more or less fits a pocket like structure in another Hemoglobin molecule in the cell. During low oxygen tension, the hemoglobin molecules polymerize, or get attached to one another forming a network of mis-shaped, stiff and distorted cells. These cells are called Sickle Cells.
What else can I help you with?
Sickle-cell anemia is an example of a point-mutation?
An example of point-mutation is sickle-cell anemia. Sickle-cell disease is hereditary.
Is sickle cell an example of codominance in genetics?
Yes, sickle cell anemia is an example of codominance in genetics.
Is sickle cell anemia a point mutation?
An example of point-mutation is sickle-cell anemia. Sickle-cell disease is hereditary.
Is sickle cell anemia example of poikilocytosis?
No
Can a disease cure a disease For example Can Cancer be cured by Sickle Cell Anemia?
well no cancer can not be cured by sickle celled anemia because sickle cell is the abnormalty of the shape of the cell.
What is Sickle-cell anemia is an example of?
Genetic disorder
The genetic disorder sickle cell disease is an example of heterozygous dominance?
Sickle cell disease is an example of codominance, not heterozygous dominance. In individuals who are heterozygous for the sickle cell allele, they exhibit a milder form of the disease called sickle cell trait, which demonstrates codominance of the normal and mutant hemoglobin alleles.
An example of all human cells and mutations?
Sickle-cell disease
Is sickle cell anemia an example of balanced polymorphism?
Yes. This answer is TRUE.
Why is sickle cell called a sickle cell?
The shape of the cell is misshapen.
What is an example of a human genetic disease?
Parkinsons Disease or Sickle Cell Anemia.
People with one sickle cell are not likely to get malaria what is this an example of?
Genetic drift
