variable segments of light and heavy chains
Heavy chain variable regions & light chain variable region.
A single chain variable fragment (scFv) is a type of antibody that consists of the variable regions of the heavy and light chains of an antibody linked together by a short peptide linker. This results in a single polypeptide chain that retains the antigen-binding specificity of the original antibody. ScFvs are used in various research and therapeutic applications due to their small size and modular nature.
Antibodies lack a transmembrane domain.
Each antibody has a variable region at the top of the arms of the Y-Shaped structure of the antibody. These variable regions each have a different sequence of amino acids and therefore a different structure. This means that only specific antigens can bind to the binding sites - only those with a complementary shape. The antigen fits into the binding site by induced fit. Once the antigen has bound to the antibody it forms a highly specific antigen-antibody complex. Therefore the role of the variable region is to produce a specific binding site for each type of antigen.
variable region
Domain is used to refer to the x (or the independent variable).
It is a value in the co-domain [range] of the function.
x is a letter often used as a variable. It can be in the range or the domain. However, in elementary algebra, the variable x is most often used for the domain and f(x) =y for the range.
Domain is the independent variable in an equation. It is what you put "in" the equation to get the Range.
domain
domain