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Congenital adrenal hyperplasia (CAH) refers to any of several autosomal recessive diseases resulting from mutations of genes for enzymes mediating the biochemical steps of production of cortisol from cholesterol by the adrenal glands (steroidogenesis). Most of these conditions involve excessive or deficient production of sex steroids and can alter development of primary or secondary sex characteristics in some affected infants, children, or adults. Only a small minority of people with CAH can be said to have an intersex condition, but this attracted American public attention in the late 1990s and many accounts of varying accuracy have appeared in the popular media. Approximately 95% of cases of CAH are due to 21-hydroxylase deficiency.
Examples of conditions caused by various forms of CAH: * ambiguous genitalia, in some females, such that it can be initially difficult to determine sex * vomiting due to salt-wasting leading to dehydration and death * early pubic hair and rapid growth in childhood * precocious puberty or failure of puberty to occur (sexual infantilism: absent or delayed puberty) * excessive facial hair, virilization, and/or menstrual irregularity in adolescence * infertility due to anovulation * hypertension
What else can I help you with?
Can children play sport with congenital adrenal hyperplasia?
yes i think.
What Adrenal glands disorders do you get?
Some common adrenal gland disorders include Addison's disease, Cushing's syndrome, and congenital adrenal hyperplasia. Addison's disease is characterized by insufficient production of adrenal hormones, while Cushing's syndrome is marked by excessive levels of cortisol. Congenital adrenal hyperplasia involves a group of genetic disorders affecting the adrenal glands' ability to produce hormones like cortisol and aldosterone.
What condition do you have when your Adrenaline glands cause too much testosterone?
Congenital adrenal hyperplasia.
Who is the carrier in Congenital Adrenal Hyperplasia?
Congenital Adrenal Hyperplasia is an autosomal recessive disorder, which means that it typically requires both parents to pass on a copy of the faulty gene for a child to be affected. Carriers of the condition usually do not show symptoms themselves but can pass on the gene to their offspring.
Does congenital hyperplasia cause short stature?
Children with Congenital Adrenal Hyperplasia (CAH) typically reach an adult height that is well below those non affected. Treatment includes replacing the deficient hormones.
What are some of the common symptoms of congenital adrenal hyperplasia?
Symptoms of Congenital adrenal hyperplasia in girls is abnormal looking genitals including an enlarged clitoris. This condition is not always apparent in baby boys. Other symptoms include early puberty, irregular menstrual cycles, infertility, and rapid growth during childhood.
What is the medical term for excessive development of adrenal cortex?
The medical term for excessive development of the adrenal cortex is "adrenal hyperplasia." This condition can lead to an overproduction of adrenal hormones, which may result in various health issues, including hormonal imbalances. Congenital adrenal hyperplasia (CAH) is a specific form often diagnosed at birth and is caused by genetic enzyme deficiencies.
What is the cause of adrenal hyperplasia?
Adrenal hyperplasia is primarily caused by genetic mutations that affect the adrenal glands' ability to produce hormones. The most common form, congenital adrenal hyperplasia (CAH), is usually due to a deficiency in the enzyme 21-hydroxylase, leading to an imbalance in steroid hormone production. This results in excess androgens and can cause various symptoms, including ambiguous genitalia in newborns and precocious puberty. Other less common forms may involve different enzyme deficiencies or genetic factors affecting adrenal function.
What has the author Maria I New written?
Maria I. New has written: 'Congenital adrenal hyperplasia' -- subject(s): Adrenogenital syndrome, Pediatric endocrinology 'The Genetics of Endocrine Disorders (Contemporary Endocrinology)'
What is an abnormal condition of excess androgen secretion observed primarily in woman?
Excess androgen secretion may be related to polycystic ovarian syndrome, which affects one in twenty women. Another cause may be congenital adrenal hyperplasia.
Who discovered adrenal hyperplasia?
Adrenal hyperplasia wasn't discovered by a single person as it refers to a group of disorders in which the adrenal glands produce excess hormones. The condition was identified through clinical observation and research by multiple scientists and physicians over time.
How is adrenal virilism treated?
Adrenal virilism caused by adrenal hyperplasia is treated with daily doses of a glucocorticoid. Usually prednisone is the drug of choice, but in infants hydrocortisone is usually given
