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Focal segmental glomerulosclerosis is scar tissue that forms in parts of the kidney called glomeruli. The glomeruli serve as filters, helping rid the body of unnecessary or harmful substances."Focal" means that some of the glomeruli become scarred, while others remain normal. "Segmental" means that only part of an individual glomerulus is damaged. Men and boys are at a slightly larger risk than women and girls. This condition causes 10-15% of all cases of nephrotic syndrome.

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