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Autoimmune diseases arise from an overactive immune response of the body against substances and tissues normally present in the body. In other words, the body actually attacks its own cells. The immune system mistakes some part of the body as a pathogen and attacks it. In otherwords, our own body's ceels can not recognise a liitle changesells of the same type. This may be restricted to certain organs (e.g. in chagas disease) or involve a particular tissue in different places (e.g. Goodpasture's disease which may affect the basement membrane in both the lung and the kidney).

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