A form of skin cancer. The body is made up of many types of cells. Normally, cells grow, divide and die. Sometimes, cells mutate (change) and begin to grow and divide more quickly than normal cells. Rather than dying, these abnormal cells clump together to form tumors. If these tumors are cancerous (also called "malignant"), they can invade and kill your body's healthy tissues. From these tumors, cancer cells can metastasize (spread) and form new tumors in other parts of the body. By contrast, noncancerous tumors (also called "benign") do not spread to other parts of the body.
Melanoma is a type of skin cancer. It begins in skin cells called melanocytes (say: "mel-an-oh-sites"). Melanocytes produce the substance that gives your skin its color.
Most other skin cancers don't spread, but melanoma can spread through the whole body. If it is found early, it can be cured. If it is found late, it may cause death.
Melanoma is a serious form of skin cancer that develops in the cells ... tissue), lymph nodes away from the original tumor, the lungs, liver, brain, and bone.
They often look like a somewhat larger mole, the difference with a regular mole being that it is often larger, more fiery-looking and sometimes itchy, and it will usually grow in size over time.
With influenza vaccinations, if the child had the vaccine given by injection (flu shot) and not by nasal spray, then the vaccine would have been made from inactivated viruses and not from weakened, but still live, viruses. The live virus vaccines are the ones that have potential infection problems for the immunocompromised person.
You are mixiing two ideas, like is blue warm? Cancerious growths are either benign or malignant. ( I will not discuss other types of tumors here). Gene expression is either dominant or ressive. ( There are other types of gene's also ). The lack of Ozone in Punta Areanus, Chile, causes a malignant form of skin cancer called Melonoma, and it kills a significant number of people. ( over 200 in a city with 130,000 people ).
Unfortunately, the disadvantages far outweight the advantages in respect of sunbeds, there is a risk of various skin diseases, such as melonoma, and regrettably, the risk is now becoming more and more as there are far more of the general public ignoring the warnings and continuing to use sunbeds. Frequent use of the sunbed will eventually result in the aging process picking up speed where your skill will be left with wrinkled skin earlier on in your life, rather than in your 40's-50's (when the skin should be starting to age).
They used to say that a good healthy tan was good for you. It is however, not.The darkening of the skin is actually the cells burning or toasting. Nice thought huh? Too much sun can and does promote skin cancer which can be life threatening. Melonoma is a very dangerous type of skin cancer that if left untreated and checked can kill.
Melanoma is a type of skin cancer that develops in the melanocytes, which are the pigment-producing cells in the skin. The exact cause of melanoma is not fully understood, but it is believed to be a combination of genetic predisposition and exposure to ultraviolet (UV) radiation from the sun or artificial sources such as tanning beds. Here are some factors that may increase the risk of developing melanoma: UV Radiation Exposure: Exposure to UV radiation from the sun or indoor tanning devices is a major risk factor for melanoma. UV radiation damages the DNA in skin cells, increasing the likelihood of mutations that can lead to the development of cancerous growths. Fair Skin: People with fair skin, light hair, and light eyes are at higher risk of developing melanoma because they have less melanin, which provides natural protection against UV radiation. History of Sunburns: A history of severe sunburns, especially during childhood or adolescence, can increase the risk of melanoma later in life. Sunburns indicate overexposure to UV radiation, which can damage the DNA in skin cells and increase the risk of cancer. Family History: Individuals with a family history of melanoma or other types of skin cancer have an increased risk of developing melanoma themselves. Certain genetic mutations may predispose individuals to melanoma, although most cases of melanoma occur in people without a family history of the disease. Moles: Having numerous moles (nevi) or atypical moles (dysplastic nevi) may increase the risk of melanoma. Changes in the size, shape, color, or texture of moles may indicate the development of melanoma or other skin cancers. Weakened Immune System: People with weakened immune systems, such as those with HIV/AIDS or who are undergoing immunosuppressive therapy, may have an increased risk of developing melanoma. Age: While melanoma can occur at any age, the risk increases with age, with most cases diagnosed in adults over the age of 50. It's important to note that while these factors may increase the risk of developing melanoma, not everyone with these risk factors will develop the disease. Additionally, melanoma can occur in individuals without any known risk factors. Practicing sun safety, including wearing sunscreen, protective clothing, and seeking shade, is essential for reducing the risk of melanoma and other types of skin cancer. Regular skin self-examinations and annual skin checks by a healthcare provider can help detect melanoma early when it is most treatable. If you notice any changes in your skin, such as new moles, changes in existing moles, or other suspicious growths, it's important to seek prompt medical attention.
A number of rare mutations, which often run in families, are known to greatly increase one's susceptibility to melanoma. One class of mutations affects the gene CDKN2A[disambiguation needed]. An alternative reading frame mutation in this gene leads to the destabilization of p53, a transcription factor involved in apoptosis and in fifty percent of human cancers. Another mutation in the same gene results in a non-functional inhibitor of CDK4, a [cyclin-dependent kinase] that promotes cell division. Mutations that cause the skin condition Xeroderma Pigmentosum (XP) also seriously predispose one to melanoma. Scattered throughout the genome, these mutations reduce a cell's ability to repair DNA. Both CDKN2A and XP mutations are highly penetrant[clarification needed].Familial melanoma is genetically heterogeneous,[8] and loci for familial melanoma have been identified on the chromosome arms 1p, 9p and 12q. Multiple genetic events have been related to the pathogenesis (disease development) of melanoma.[9] The multiple tumor suppressor 1 (CDKN2A/MTS1) gene encodes p16INK4a - a low-molecular weight protein inhibitor ofcyclin-dependent protein kinases (CDKs) - which has been localised to the p21 region of human chromosome 9.[10]Other mutations confer lower risk but are more prevalent in the population. People with mutations in the MC1R gene, for example, are two to four times more likely to develop melanoma than those with two wild-type (typical unaffected type) copies of the gene. MC1R mutations are very common; in fact, all people with red hair have a mutated copy of the gene.Two-gene models of melanoma risk have already been created,[citation needed] and in the future, researchers hope to create genome-scale models that will allow them to predict a patient's risk of developing melanoma based on his or her genotype.In addition to identifying high-risk patients, researchers want to identify high-risk lesions (abnormal area of tissue) within a given patient. Many new technologies, such as optical coherence tomography(OCT), are being developed to accomplish this. OCT allows pathologists to view 3-D reconstructions of the skin and offers more resolution than past techniques could provide. In vivoconfocal microscopy and fluorescently tagged antibodies are also proving to be valuable diagnostic tools.Mutation of the MDM2 SNP309 gene is associated with increased risk of melanoma in younger women.[11