What is mode of action of HIV?

Answer 1

The mode of action of HIV involves the virus infecting host T-cells, specifically CD4+ T-lymphocytes. Upon entry, HIV uses its envelope proteins to bind to CD4 receptors and co-receptors on the T-cell surface, facilitating fusion and entry into the cell. Once inside, the viral RNA is reverse transcribed into DNA, which integrates into the host genome, allowing the virus to hijack the cell's machinery to produce new viral particles. This process ultimately leads to the depletion of CD4+ T-cells, compromising the immune system and leading to AIDS.