Several different substances can be toxic to the kidneys. These include: antibiotics, primarily aminoglycosides, sulphonamides, amphotericin B, polymyxin, neomycin, bacitracin, rifampin, trimethoprim, cephaloridine, methicillin.
Damage to the kidneys is assessed through a combination of physical examination, blood tests, urine tests, and imaging procedures. Diagnosis of nephrotoxic injury as the underlying cause results from a thorough investigation of.
Treatment of nephrotoxic injury takes place in the hospital and focuses on removing the toxin from the patient's system, while maintaining kidney function. Removal methods are targeted to specific toxins and may include.
The outcome of nephrotoxic injury is determined by the cause and severity of the damage. In cases where damage has not progressed beyond acute renal failure, kidney function can be fully restored once the toxin is removed from.
Symptoms of nephrotoxic injury are wide ranging and, in some cases, depend upon the type of toxin involved. In general, symptoms are similar to those of renal failure and include excess urea in the blood (azotemia), anemia.
Toxic, or damaging, to the kidney.
When taking antibiotics or analgesics, recommended dosages should be strictly followed. Also, elderly patients on these medications (for example, those taking aspirin for heart problems or NSAIDs for arthritis) should be closely monitored.
lack of blood supply to the kidneys (ischemia) use of radiocontrast agents in patients with kidney problems drug abuse or overdose long-term use of nephrotoxic medications
Serum creatinine
to remove nephrotoxic drugs or poisons from the blood in emergency situations
vancomycin before its was 'reformulated' due to its nephrotoxic side effect
No, allopurinol is not considered a nephrotoxic agent. In fact, it is often prescribed to prevent gout attacks by reducing uric acid levels in the body. However, allopurinol can rarely cause kidney problems in some individuals, especially with pre-existing kidney disease.
ACE inhibitors are generally not considered nephrotoxic; in fact, they are often beneficial for kidney health, especially in patients with hypertension or diabetes. However, they can potentially cause a reversible increase in serum creatinine levels, particularly in individuals with pre-existing renal impairment or renal artery stenosis. Careful monitoring and dose adjustments are recommended in these populations to mitigate any adverse effects on kidney function.