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Polyomavirus is a group of small, non-enveloped DNA viruses that can cause infections in humans and animals. In humans, the most well-known types are JC virus and BK virus, which typically remain dormant in the body after initial infection and can reactivate under certain conditions, particularly in immunocompromised individuals. The disease is primarily spread through respiratory droplets or urine, and it can also be transmitted through contact with contaminated surfaces. Most healthy individuals do not experience symptoms, but those with weakened immune systems may develop serious complications.

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