Stiff person syndrome (SPS) is an extremely rare progressive neurological disorder characterized by persistent rigidity and spasms of certain voluntary muscles, especially those of legs and feet.
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Stiff person syndrome is believed to be caused by an autoimmune response that affects the muscles and nerves, leading to stiffness and spasms. It is thought that a combination of genetic predisposition and environmental triggers play a role in the development of this rare neurological disorder.
"Stiff Man Syndrome" now usually called "Stiff Person Syndrome" is a rare disease of the nervous system that causes progressively severe muscle stiffness in the spine and legs. It is thought to be caused by an autoimmune disorder, where the enzyme responsible for making certain neurotransmitters is destroyed by the immune system. Stiff person syndrome is very rare, so it is difficult to determine the exact prevalence of the disease. However, estimates are about 1 in 1 million people will get this disease. It is more common in diabetics, about 1 in 10 thousand people with diabetes will be affected.
There is no cure for SPS and the long-term prognosis is variable. Many patients have a slow course of the disorder that is mostly without symptoms, punctuated by occasional episodes of stiffness.
Stiff Person Syndrome (SPS) can exhibit a variable course, and some patients may experience periods of remission where symptoms lessen or stabilize. However, remission is not guaranteed for everyone, and symptoms can relapse or worsen over time. Treatment options, including medications and therapies, may help manage symptoms and potentially prolong periods of remission. It's essential for patients to work closely with their healthcare providers to tailor treatment plans to their specific needs.
Sjogren-Larsson syndrome is an inherited condition resulting in thickened, dry, rough skin (ichthyosis), mental retardation , and stiff, rigid muscles (spasticity ).
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Carpel tunnel syndrome causes a wrist and hand to be stiff and sore. Tendonitis of the wrist, sprains, and arthritis can also cause a hand and wrist to swell, be sore, and stiff.
The word stiff is usually an adjective, so would have no plural. The colloquial noun "stiff" (a corpse, or a boring person) would have the plural "stiffs."
An asperger is an informal term for a person who has Asperger's syndrome.
Cardiac amyloidosis or "stiff heart syndrome" is a disorder that is caused by abnormal protein deposits in the heart tissue, making it difficult for the heart to function properly. Symptoms include excessive urination, fatigue, shortness of breath, swelling of the abdomen and heart palpitations.