(medicine) A hereditary form of hemolytic anemia resulting from a defective synthesis of hemoglobin: thalassemia major is the homozygous state accompanied by clinical illness, and thalassemia minor is the heterozygous state and may not have evident clinical manifestations. Also known as Mediterranean anemia.
Alpha thalassemia silent carrierAlpha thalassemia minor, also called alpha thalassemia traitHemoglobin H diseaseAlpha thalassemia major, also called hydrops fetalisBeta thalassemia minor, also called beta thalassemia traitBeta thalassemia intermediaBeta thalassemia major, also called Cooley's anemia or beta-zero (ß0) thalassemiaBeta-plus (ß+) thalassemiaMediterranean anemia
Thalassemia is an autosmal recessive blood disease. That means that it is an inherited disease. Thalassemia in more common in Mediteranian people.
Thalassemia is classified mainly into two types: alpha thalassemia and beta thalassemia, based on which globin chain is affected. Alpha thalassemia occurs due to mutations in the alpha-globin genes, while beta thalassemia results from mutations in the beta-globin genes. Each type can further be categorized into various subtypes based on the severity of the condition, such as thalassemia minor (trait) and thalassemia major (Cooley's anemia). The classification helps determine the appropriate management and treatment strategies for affected individuals.
Yes, A "carrier" of alpha thalassemia and of beta thalassemia can marry, but not to someone with any hemoglobinopathy. Prof. Kornfeld Pal
No. A minor form of the blood disorder thalassemia is when you inherited just one beta thalassemia gene, along with a normal beta-chain gene. This manifests as mild anaemia with a slight lowering of the hemoglobin level in the blood. No treatment is require. By contrast, a thalassemia major, also known as Cooley's Disease, is when one is born with two genes for beta thalassemia and no normal beta-chain gene. This is a serious disorder.
If you have Thalassemia major but your boyfriend is not a carrier then the child will be born a healthy carrier (thalassemia minor) but shouldn't need blood transfusions. If your boyfriend is a carrier then you would have a 50% chance of having a child with thalassemia major like you do.
yes
Those with thalassemia can expect to live until they are 50 or more.
A carrier of thalassemia, often referred to as having thalassemia trait, is an individual who possesses one normal hemoglobin gene and one mutated gene associated with thalassemia. This genetic condition typically does not cause significant health issues, but carriers can pass the mutated gene to their offspring. If both parents are carriers, there is a risk of having children with more severe forms of thalassemia, which can lead to serious health complications. Testing for thalassemia carriers is important for family planning and genetic counseling.
have seen one of my friends sister had kid and all normal no complications...not thalassemia either.........beta and alpha i think there is 25% normal chance
Hepatomegaly in thalassemia occures as aresult of engorgement of hepatic paranchymal and phagocytic cells with hemosiderin deposits.
There are several types of Thalassemia. It's believed to have originated in the Middle East & the Mediterranean areas.