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Complement is a protein made in the innate immune system that embeds itself in the membrane of bacteria, leaving a hole through which the cytoplasm escapes killing the bacterial cell.

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What is the role of complement system in immune response?

The role of a complement system in immune response is to make sure that no bad cells penetrate the immune system. A complement system of immunization might be a series of shots, like booster shots for immunizations.


What is C3 convertase?

Humans have both an "innate" and an "adaptive" immune system. There are a number of proteins circulating in the blood as part of the complement system that belongs to the innate immune system (although the adaptive system can activate it as well). Normally, the complement proteins are inactive. When the immune system detects some threat, the complement system is triggered and the circulating proteins are chemically split into smaller components. C3 convertases are chemicals that cleave C3 complement into breakdown products in both the "classical" and the "alternative" pathways of the complement system.


What plasma proteins are complement proteins?

Complement proteins are a series of immune proteins that carry out complement cascade reactions. These proteins are helping the immune system to lean up from the cells. complement proteins are not antibodies.


What is complement opsonization?

Complement opsonization is a process in the immune response where complement proteins, part of the immune system, bind to the surface of pathogens such as bacteria. This binding enhances the ability of immune cells, like phagocytes, to recognize and engulf the pathogens more efficiently. The opsonization acts as a signal that marks the pathogens for destruction, facilitating their clearance from the body. Overall, it plays a crucial role in the innate immune defense against infections.


What is the immune disorder that occurs when the production or activity of immune cells or complement is abnormal?

The immune disorder that occurs when the production or activity of immune cells or complement is abnormal is called primary immunodeficiency. It is a group of genetic disorders that affect the immune system's ability to effectively defend the body against infections. This can lead to recurrent or severe infections and other immune-related complications.


If complement and SRBC added and hemolysis occur how you will interpretate?

If complement and SRBC are added and hemolysis occurs, it indicates that the complement system is functioning properly. The lysis of the SRBCs suggests that the complement system has been activated in response to the foreign cells, resulting in their destruction. This can be used as an assay to assess the activity of the complement system.


What are compliment proteins?

Complement proteins are a group of proteins in the immune system that work together to enhance the body's ability to fight infections. They can help to attract immune cells to the site of infection, stimulate inflammation, and destroy pathogens by forming membrane attack complexes. Complement proteins play a critical role in the innate immune response.


What is the alternative pathway complement and how does it function in the immune system?

The alternative pathway complement is a part of the immune system that helps to identify and destroy harmful pathogens like bacteria. It works by activating proteins that form a complex chain reaction, leading to the destruction of the pathogen. This pathway is important for the body's defense against infections.


How does the innate immune system interact with the adaptive immune system?

The complement system is a series of about 20 proteins that are involved in a cascade effect during an immune response. Complement is generally divided up into 3 pathways: classical, lectin, alternate. The classical pathway involves a complement protein binding to an antigen-antibody complex (and thus its role in adaptive immunity). Whereas in the alternate pathway, complement (C3) binds directly to the foreign cell( usaully bacteria). Thus its repsonse is non specific and therefore is also part of the innate imune system.


What are complement deficiencies?

Complement deficiencies are a group of disorders in which there is a reduced level of specific proteins, complement, involved in proper immune functioning.


What system involves plasma proteins activated when they contact a bacterial cell?

The complement system is made up of a large number of plasma proteins. They react with one another to opsonize pathogens and induce a series of inflammatory responses that help to fight infection.


What is activation of complement?

Activation of complement refers to a series of biochemical reactions involving a group of proteins in the immune system, known as complement proteins. These proteins work together to enhance the ability of antibodies and phagocytic cells to clear pathogens, promote inflammation, and directly lyse bacteria. The complement system can be activated via three pathways: the classical, lectin, and alternative pathways, each triggered by different immune signals. Ultimately, this activation leads to the formation of the membrane attack complex (MAC), which can puncture the cell membranes of pathogens.