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-the principle of antigen-antibody reaction is a process of the immune system in which immunoglobulin-coated B cells recognize a specific antigen and stimulate antibody production. T cells also play an essential role in the reaction. An antigen-antibody reaction begins with the binding of antigens to antibodies to form antigen-antibody complexes. These complexes may render toxic antigens harmless (neutralization), agglutinize antigens on the surface of microorganisms, or activate the complement system by exposing the complement binding sites on antibodies. Certain complement protein molecules immediately bind to these sites and trigger the activity of the other complement protein molecules, which cause antigen-bearing cells to lyse. Antigen-antibody reactions may start immediately with antigen contact or as much as 48 hours later. They normally produce immunity but may also be responsible for allergy, autoimmunity, and fetomaternal hematologic incompatibility. In the immediate allergic response, the antigen-antibody reaction activates certain enzymes and causes an imbalance between those enzymes and their inhibitors

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16y ago

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