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The exact causative agent of Parkinson's disease is not fully understood, but it is primarily associated with the degeneration of dopamine-producing neurons in the substantia nigra region of the brain. Genetic factors, environmental toxins, and oxidative stress are believed to contribute to this neurodegeneration. Certain genetic mutations, such as those in the SNCA and LRRK2 genes, have also been linked to familial forms of the disease. Overall, Parkinson's disease likely results from a complex interplay of genetic and environmental influences.

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