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Down's Syndrome is caused due to the presence of an extra 21st chromosome, resulting in 3 sets of 21st chromosome instead of just 2. This is because during Anaphase II of Meiosis II non-disjunction occurs and instead of one 21st chromosome going into each gamete, both go into one of the gametes and none goes into the other. When a normal gamete fuses with the gamete with an extra21st chromosome, it forms a zygote with 3 sets of 21st chromosome instead of 2 and that is known as Down's Syndrome.
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If a child is born with down syndrome when did the mutation occur?
During meiosis
Which stage of meiosis causes Down syndrome?
Mistakes in meiosis may cause Down syndrome. The error happens when the chromosomes segregate into the gametes. The egg or sperm may have too many or too few chromosomes. Down syndrome has an extra chromosome in the 21st pair.
Down Syndrome most often occurs when-?
Down Syndrome often occurs when chromosomes fail to separate properly during meiosis.
What is a genetic condition that can result when chromosomes don't separate correctly during meiosis?
Trisomy 21 (Down's syndrome), Turner's syndrome (XO), and Klinefelter's syndrome (XXY) are a few examples of genetic disorders that can result when chromosomes don't separate correctly during meiosis.
What is the consequence of non-disjunction during meiosis?
Non-disjunction during meiosis can lead to the production of gametes with an abnormal number of chromosomes, which can result in genetic disorders such as Down syndrome.
What are the consequences of the failure of chromosomes to separate properly during meiosis?
When chromosomes fail to separate correctly during meiosis, it can lead to genetic disorders in offspring, such as Down syndrome or Turner syndrome. This can result in physical and developmental abnormalities, impacting the health and well-being of the individual.
When a child has Trisomy when does the mutation occur?
during meiosis
How are cells of a person with Down syndrome different from those of a person without the disorder?
In Down syndrome, a person's cells have an extra copy of chromosome 21. In other words, instead of a pair of chromosomes, a person with Down syndrome has three of that chromosome. Down syndrome most often occurs when chromosomes fail to separate properly during meiosis. People with Down syndrome have a degree of mental retardation. Heart defects are also common, but can be treated.
What is the medical term meaning abnormal condition of meiosis?
The medical term for an abnormal condition of meiosis is meiotic non-disjunction, which refers to the failure of chromosomes to separate properly during meiosis, resulting in an abnormal number of chromosomes in the resulting gametes. This can lead to conditions such as Down syndrome.
Can medication for gallstones during pregnancy cause Down syndrome?
See the Related Link to a very good FAQ on the causes of Down syndrome.
Which is the failure to segregate during meiosis?
Nondisjunction is the failure to segregate homologous chromosomes or sister chromatids properly during meiosis, leading to an incorrect number of chromosomes in the resulting gametes. This can result in genetic disorders such as Down syndrome.
What is the failure of chromosome pairs to separate properly during meiosis?
The failure of chromosome pairs to separate properly during meiosis is called nondisjunction. This can lead to an incorrect number of chromosomes in the resulting gametes, causing aneuploidy in the offspring. Aneuploidy can result in genetic disorders such as Down syndrome.
