Megaloblasitc anemia refers to the abnormal enlargement of RBCs rendering them useless and subject to hemolysis, therefore the bone marrow must up regulate its hematopoietic stem cell production and in particular the differentiation of reticularcytes to counter the anemia.
Pernicious anemia
Alchohol can be associated with anemia. For example, alcoholic liver damage can be a cause of megaloblastic anaemia Alchohol can be associated with anemia. For example, alcoholic liver damage can be a cause of megaloblastic anaemia
Megaloblastic (Macrocytic) Anemia. Basically the Red Blood Cells have a larger volume (MCV).
Megaloblastic anemia is a blood disorder. It is marked by the appearance of very large red blood cells in addition to anemia, which involves the loss of red blood cells that transport oxygen through the body.
_ is caused by protozoan plasmodium
Vitamin B12 deficiency anemia is another type of megaloblastic anemia that develops when the body doesn't absorb enough of this nutrient.
megaloblastic or macrocytic nucleatd cells.
Vitamin B12 anemia, specifically known as pernicious anemia or vitamin B12 deficiency anemia, occurs due to insufficient vitamin B12, often due to malabsorption, leading to the production of large, immature red blood cells. Megaloblastic anemia, on the other hand, is a broader category that includes any anemia characterized by the presence of megaloblasts in the bone marrow, typically caused by deficiencies in either vitamin B12 or folate. While both result in similar symptoms and large red blood cells, the underlying causes differ, with megaloblastic anemia encompassing a wider range of deficiencies beyond just vitamin B12.
Megaloblastic anemia results from a deficiency of vitamin B12 or folic acid, both of which play a crucial role in DNA synthesis and red blood cell production. This deficiency leads to the production of abnormally large and immature red blood cells, causing anemia.
Macrocytic anemia is under 281.9 in the ICD-9. Macrocytic anemia does not have its own code. It shares that code with several other types of unspecified deficiency anemia, including dimorphic, megaloblastic NOS, nutritional NOS, and simple chronic.
Deficiency leads to pernicious anaemia when immature red blood cell precursors are released into the bloodstream, and there is degeneration of the spinal cord.
Macrocytic anemia is under 281.9 in the ICD-9. Macrocytic anemia does not have its own code. It shares that code with several other types of unspecified deficiency anemia, including dimorphic, megaloblastic NOS, nutritional NOS, and simple chronic.