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After infection, the CD4 count measured in blood generally reduces in the first month or two and then recovers, but not to the pre-infection level.

Then, usually over many years the CD4 count reduces until HIV advances to cause symptoms.

Anti-retroviral treatment stops the decline in CD4 cells which then usually recover and get stronger again.

With HIV there is a lot of individual variability in how fast this takes. Some people need treatment soon after infection and other can still have a strong CD4 count after 15 years without treatment.

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14y ago

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