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isoform and isoenzymes are two different words for the same thing.

Creatine kinase is an enzyme found in muscle and brain tissues. The different isoenzymes include MM, MB, and BB. The MM isoform is found primarily in skeletal muscle, the BB isoform is found primarily in brain tissue, and the MB isoform is found primarily in cardiac muscle.

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How is creatine kinase produced in the body?

Creatine kinase (CK) is produced primarily in muscle, brain, and heart tissues, where it plays a crucial role in energy metabolism. It catalyzes the conversion of creatine and ATP (adenosine triphosphate) into phosphocreatine and ADP (adenosine diphosphate), facilitating the rapid regeneration of ATP during high-energy demands. The enzyme is synthesized from specific genes, with different isoforms (such as CK-MM in muscle and CK-MB in heart) produced depending on the tissue type. CK levels can be measured in the blood, and elevated levels often indicate muscle damage or stress.


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