As the afferent arteriole dilates it exposes the glomerulus to an increased blood pressure, closer and closer to that of the full systemic blood pressure. This increases GFR and Glomerular pressure.
-6th Year Medical Student
reducing afferent arteriole radius decreases filtration rate
Constricted arterioles in the glomerulus can lead to a decrease in the glomerular filtration rate (GFR) by reducing the amount of blood flow entering the glomerulus. This can result in decreased filtration of waste and reduced urine production.
increase afferent radius or decrease efferent radius depending on the degree of change in blood pressure
Efferent means going away from and afferent is going toward. The afferent arteriole of the kidney carrys blood toward the glomerulus, whereas the efferent arteriole carrys blood away from the glomerulus.
In the presence of renal artery stenosis, the resistance in the afferent arteriole is increased. As compensation, Angiotensin II acts to constrict the efferent arteriole in order to achieve adequate profusion of the glomerulus. ACE inhibitors block the conversion of angiotensin I into angiotensin II. Without its vasoconstrictive effect, the efferent arteriole becomes dilated. This leads to a drop in GFR and may lead to renal failure.
Sympathetic stimulation causes vasoconstriction of the afferent arterioles in the kidneys. This response reduces blood flow into the glomeruli, which can decrease glomerular filtration rate (GFR). The effect is part of the body's mechanism to prioritize blood flow to vital organs during stress or low blood volume situations. Ultimately, this helps conserve water and maintain blood pressure.
Keith Whelpdale has written: 'The effect of primary afferent denervation on wound healing'
· Afferent and efferent divisions are:o Sensory (afferent) Division§ Somatic afferent nerves - carry impulses from skin, skeletal muscles, and joints to the CNS§ Visceral afferent nerves - transmit impulses from visceral organs to the CNSo Motor (efferent) Division§ Transmits impulses from the CNS to effector organs, muscles and glands, to effect (bring about) a motor responseAfferent nerves are the one that carry the information from periphery to central nervous system for further processing. While efferent nerves carry the processed information from central nervous system towards the periphery for action.
Afferent refers to pathways leading to the cortex (ie, sensory). Efferent are pathways leading away (ie, motor). You are *affected* by a situation, you *effect* change on someone else.
lesser data traffic
Reducing stress in the steel.
Glomerular hydrostatic pressure is the primary driving force for filtration rate in the kidneys. An increase in glomerular hydrostatic pressure will increase the rate of filtration by pushing more fluid and solutes out of the blood and into the renal tubules. Conversely, a decrease in glomerular hydrostatic pressure will decrease the filtration rate.