What is the etiology of Pregnancy induced hypertension?

Answer 1

In the first, the initiating cause results in the placenta producing factors (e.g., specific proteins, placental "debris") that enter the maternal circulation and are believed responsible for producing the next stage. This is the second stage, which results in the overt maternal "disease" (high blood pressure, kidney, liver and coagulation abnormalities). The overt disease depends not only on the action of the circulating factors from the placenta, but also the health of the mother, including diseases that may affect the vasculature (such as preexisting cardiovascular, renal, metabolic, and genetic factors; and obesity).

A promising area of recent research involves the role of proteins produced by the placenta that inhibit angiogenesis (the production of new blood vessels). Two of these "antiangiogenic factors" (soluble Fms-like tyrosine kinase-1, and soluble endoglin) have been shown to produce a preeclampsia like disease in rodents. Their concentrations rise in the mother's circulation weeks to months before the disease manifests. Placentas of women destined to develop preeclampsia overproduce these proteins that then enter the mother's circulation. Neutralizing their actions is now being investigated in animal models, and in some studies has reversed the disease in rodents. . Excitement regarding these interventions is tempered by a limited understanding of the functional role of antiangiogenic substances in normal pregnancy.

If the ability of these antiangiogenic proteins to cause preeclampsia is confirmed by research in humans, why the placenta overproduces them remains unknown. Hence, many of the other areas of investigation mentioned above may be important. Preeclampsia may have multiple causes, and other leads are being investigated, including prostaglandins, digoxin-like molecules, immunological mechanisms, autoantibodies that trigger receptors that lead to vessel constriction (agonistic autoantibodies to the angiotensin 1 receptor), oxidative stress, mitochondrial pathology, the impact of hypertension and prehypertension on endovascular health, and genes sensitive to low oxygen environments.

Answer 2

Pregnancy induced hypertension is seen in cases of EPH syndromes (Oedema-Edema, Protienuria and Hypertension). Its mailnly due to created pressure on some vessels due to pregnancy (volume and weight of the fetus in the abdomen)

Answer 3

Pregnancy can induce high blood pressure. If this is a new development and it occurs after 20 weeks of pregnancy and no other abnormalities (such as protein in the urine) are detected it is considered to be Pregnancy induced hypertension (gestational hypertension). This normally goes away (usually within six weeks of having the baby).

In some cases though, the high blood pressure may persist after the pregnancy and it will need to be treated as any other case.

Sometimes, in addition to the raised blood pressure other abnormalities are noted - in such a case your diagnosis is pre-eclampsia which needs careful watching.
PIH is a hypertensive condition brought about by pregnancy common in primigravida and will be resolve after giving birth.

Answer 4

Gestational hypertension, also referred to sometimes as pregnancy induced hypertension (PIH) is a condition of high blood pressure during pregnancy. Gestational hypertension can lead to a serious condition called preeclampsia (also sometimes referred to as toxemia). Hypertension during pregnancy affects about 6-8% of all pregnant women.

Answer 5

The term you are looking for is pre-eclampsica.

Answer 6

Gestational hypertension.