platelets help in conversion of fibrinogen, a soluble plasma protein into insoluble form fibrin. The fibrin threads entangle with red blood cells and other platelets in the are of damaged tissue, ultimately forming a blood clot. When fibrinogen is transformed into fibrin and its fibires separate the underlying matter is called serum.
Platelet Count
Platelet function studies are typically collected in a blue-top tube (sodium citrate) to prevent clotting and maintain the function of platelets for analysis.
Iron
Platelet function disorders can be inherited, but they may also occur as a symptom of acquired diseases or as a side effect of certain drugs, including aspirin.
it helps in platelet agregassion
Thromboxane is a potent platelet agregator
The outcome depends on the specific disorder and the severity of its symptoms. Platelet function disorders range from life-threatening conditions to easily treated or little-noticed problems.
Inherited platelet function disorders cannot be prevented except by genetic counseling ; however, some acquired function disorders may be guarded against by avoiding substances that trigger the disorder.
MPV is an acronym for mean platelet volume. The MPV is a measurement of the average size of platelets. A high MPV usually means that there is good platelet function.
A light blue top tube containing sodium citrate is typically used to collect blood for platelet function studies. The sodium citrate helps prevent blood clotting by binding calcium ions.
Yes, a platelet count of 286,000 platelets per microliter (often reported as 286) is considered normal for adult men. The normal range for platelet counts typically falls between 150,000 and 450,000 platelets per microliter. Therefore, a count of 286,000 is well within this range and indicates normal platelet function.
To calculate the mean platelet volume (MPV), you need a complete blood count (CBC) test that provides the platelet count and the volume of platelets. MPV is typically calculated by dividing the total volume of platelets by the number of platelets present in the sample. The formula can be expressed as MPV = (Total platelet volume / Total platelet count). This value helps assess platelet function and can be an indicator of various health conditions.