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Schizophrenia and Parkinson's disease both involve dysregulation of dopamine, a neurotransmitter critical for mood and movement. While schizophrenia is characterized by excessive dopamine activity in certain brain regions, Parkinson's disease is associated with a deficit of dopamine due to the degeneration of dopaminergic neurons. Additionally, some antipsychotic medications used to treat schizophrenia can exacerbate Parkinsonian symptoms, highlighting the complex interplay between these disorders. Research also indicates a potential genetic and neurobiological overlap, suggesting shared pathways in their pathology.

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2mo ago

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